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Retatrutide, a GIP, GLP 1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double blind, placebo and active controlled, parallel group, phase 2 trial conducted in the USA The Lancet 3 questions to consider: , 1. If other countries treat GLP 1s as risky enough to restrict, why dont we?, 2. Who benefits from a system with fewer restrictions and who carries the risk?, 3. Does Mapping the effectiveness and risks of GLP 1 receptor agonists Nature Medicine Ozempic's patent problem: how Novo Nordisk lost control of a blockbuster drug. Demand for GLP 1 weight loss drugs has exploded, turning Ozempic into a $40bn+ revenue engine for Novo Nordisk. But, despite Natural GLP 1 Activation Protocol PureHealth Research GLP 1 Medications for Weight Loss in Breast Cancer Patients Dana Farber Cancer Institute
01053-X/asset/68ad1d8b-bb7e-4ca0-8f89-99384d885ca3/main.assets/gr2.jpg "Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA - The Lancet")
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Best in 7 days
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4.8 ★★★★★
Based on 461 reviews
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Product Reviews
★★★★★ 5
Absolutely Love This Receiver
The Onkyo TX‑NR7100 has completely transformed my home theater. The sound quality is rich, detailed, and powerful, and the 9.2‑channel setup gives movies and music a level of immersion I didn’t realize I was missing. Dirac Live right out of the box is a huge win — the room correction made an immediate, noticeable improvement.
Setup was smooth, the interface is clean, and everything from streaming to switching inputs feels fast and reliable. It also plays perfectly with the rest of my system, and the THX certification really shows in how cinematic everything sounds.
I absolutely love this receiver. It’s one of those upgrades that makes you wonder why you didn’t do it sooner.
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Reviewed in the United States on February 20, 2026
★★★★★ 5
Incredible 9.2 Surround receiver at an unbeatable price.
I may return at a future date to give a more complete review, but others that are much more knowledgeable about audio equipment than I have already done so.
For me, the Onkyo (Onkyo TX-NR7100 9.2-Channel 8K/4K Network A/V Receiver) replaced a much older (2001) TX DS787 5.1 100 W Surround receiver that listed new for around $1050. I probably didn't pay quite that much but certainly something near $900. It was great for its time, perhaps even advanced with THX, Dolby, and other listening modes.
But it didn't have: HDMI inputs or outputs, any BlueTooth capability, no hard wired or WiFi connectivity or basically any operating or connection modes that most all modern receivers have. This turned into a big problem with modern LED/LCD/OLED TVs, Alexa and other now common devices.
I bought my new Onkyo TX-NR7100 from Amazon for $625. Other retailers (e.g.Best Buy) advertise it for up to $1200, so Amazon's price is outstanding. Set up was far more complicated (for me) than any previous receiver that I ever owned, mostly because there were a very large number of back panel input and output jacks, to and from the TV, as well as speaker outputs for 9.2 surround.
Suffice it to say that once everything was connected properly (I made a few mistakes along the way), I was completely thrilled. The On Screen Display, completely accessible either from the front panel or the remote was far superior to anything I had ever seen before. Literally every operating parameter is accessible to the user. And I used most of them.
It is also completely WiFi ready so my 150 Gbit home Wifi network lets it connect wirelessly and stream music error free. BlueTooth is also another way to connect almost any device to it for audio and audio/video playback if you connect the digital connections to and from a modern TV. It also speaks and listens to Alexa, although I must confess that I haven't played around with that much yet.
This is already much longer than I had intended, so let it suffice to say that the Onkyo TX-NR7100 is an absolutely incredible receiver for an incredible price. I'd give it 8 stars if I could.
JM TEPPER
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Reviewed in the United States on November 7, 2024
★★★★★ 5
Sounds great.
Just received my Onkyo TX-NR 7100, watched a few YouTube videos before it arrived, so set up was easy. Ran accuEQ, I am getting new front speakers so I’ll wait to run Dirac. After accuEQ, I still had to make a few adjustments, to the speaker levels and especially the sub. It set my subwoofer way too low. As of right now having no problems with Bluetooth. I’ve only listened to music so far, can’t wait to watch a movie. For now I have a 5.1.2. System, getting new fronts, the Klipsch r51-m’s will go to the rear surround and Klipsch r41-m’s will be my height speakers in a 5.1.4 system. So far loving this avr.
Update 2: Just calibrated with Dirac for the 6th time. They tell you if you sit in a recliner, reclined measure with it reclined. Well I measured with the chair in its upright position. It makes a huge difference I hear the surrounds much better. Btw I listen to all channel stereo, I know audiophiles say it sucks, however I listened to 2 channel stereo for 20 years, when there was nothing else. I didn’t buy a 9 channel avr to listen to 2 channel stereo. Like Randy the cheap audio man says “ audiophiles aren’t always right. If it sounds good to you, that’s all that matters.” So try calibrating in the upright position, or if you sit on a stationary chair or couch, try positioning the mic slightly forward of your listening position. It makes a huge difference. Hope this helps, enjoy.
Update:
Ok bought Klipsch rp-600m speakers for the front with 52c center. 51m surrounds, 41m rear heights. Polk owm3 front heights. Why Polk? Lighter easy to hang and as height speakers they are only there for atmos. Ran Dirac live, the application does what it would take several hours to make it sound like it does, if I even could get it to sound so good. Apple TV 4K with my Hisense U8K. The google tv interface is ok, but Apple TV is faster and easier. The Onkyo 7100 is a gem, runs pretty warm but I have it out in the open. If you are going to put in a cabinet I suggest a fan. Very happy with the whole system.
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Reviewed in the United States on January 11, 2025
★★★★★ 5
Well made, a solid connection.
Size: 6 Pairs / 12 pcs
I liked them. They really lock down on the speaker wire to make a firm connection. They seem well made and are easy to install. My system sounds great.
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Reviewed in the United States on April 1, 2026
★★★★★ 5
Works as intended
Size: 12 Pairs / 24 pcs
These banana plugs are quite easy to use, and securely connected my speaker cables to the receiver. They have a quality feel as well.
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Reviewed in the United States on July 27, 2025
